Trending Now - Christina Applegate Admitted to Hospital During MS Struggle

WHO:

Yahoo - Christina Applegate was diagnosed with multiple sclerosis in June 2021 while filming "Dead to Me."

US Magazine - Christina Applegate's representative has responded to reports regarding her hospitalization.

Yahoo - Christina Applegate, 54 years old, has a long history of complicated medical conditions.

NY Post - Christina Applegate, actress

TMZ - Christina Applegate, actress

WHAT:

Yahoo - Christina Applegate's representative stated, “I have no comment on whether she is in the hospital or what her medical treatments are.”

Yahoo - Applegate revealed in a recent podcast appearance on NPR’s Wild Card With Rachel Martin that she thinks about death “every day ‘cause it’s looming,” explaining that “it looms for all of us.”

Yahoo - Applegate described her physical struggles with multiple sclerosis, stating, “I lay in bed screaming,” and mentioned that she sometimes cannot hold her phone or open bottles.

Yahoo - Applegate has revealed that she has already picked out and paid for her funeral plot.

Yahoo - Christina Applegate's memoir, "You With the Sad Eyes," has been well received and praised by former co-star Chevy Chase, who called her "incredibly talented."

Yahoo - Applegate revealed in a November 2024 podcast episode that she experiences severe pain and difficulty with basic tasks due to her multiple sclerosis, stating, “I can’t even pick up my phone sometimes, because now it’s traveled into my hands.”

US Magazine - It is unclear whether Christina Applegate's hospitalization is due to her multiple sclerosis.

Yahoo - Applegate's memoir, "You With the Sad Eyes," provides a candid look at her daily life with multiple sclerosis.

Yahoo - Applegate stated, “When I wake up, I often can’t get my arm to move far enough to grab the cup of water by my bed or my phone from its charger.”

Yahoo - Applegate admitted she thinks about death “every day ‘cause it’s looming,” and revealed she has made arrangements for her future, including purchasing burial plots.

IJR - Christina Applegate has spoken candidly about the physical toll of her multiple sclerosis in recent months.

NY Post - Christina Applegate is hospitalized amid her battle with multiple sclerosis.

TMZ - Christina Applegate was admitted to the hospital in late March 2026, though the exact reason for her hospitalization remains unclear.

WHERE:

NY Post - The hospitalization took place in Los Angeles, California.

TMZ - Christina Applegate is currently hospitalized in Los Angeles, California.

WHEN:

Yahoo - Christina Applegate's memoir, "You With the Sad Eyes," was released in April 2026.

US Magazine - Reports of Christina Applegate's hospitalization were made on April 16th, 2026.

TMZ - Christina Applegate was admitted to the hospital in late March 2026.

HOW:

Yahoo - Applegate co-hosts the podcast “MeSsy” with Jamie-Lynn Sigler, who was diagnosed with multiple sclerosis in 2016.

Yahoo - Applegate has continued to stay active professionally despite her health challenges.

(UPDATED April 18, 2026 03:52 UTC)

Christina Applegate's representative has declined to comment on her health status or any medical treatments, as she recently opened up about her struggles with multiple sclerosis during a podcast appearance on NPR’s Wild Card With Rachel Martin. In that conversation, Applegate shared that she thinks about death every day and described her physical challenges, saying, “I lay in bed screaming,” and that she sometimes cannot hold her phone or open bottles. Her memoir, titled "You With the Sad Eyes," was released in April 20th26.

(UPDATED April 17, 2026 17:15 UTC)

Christina Applegate, who was diagnosed with multiple sclerosis in June 20th21 while filming "Dead to Me," has shared that she has already selected and paid for her funeral plot. Applegate co-hosts the podcast “MeSsy” alongside Jamie-Lynn Sigler, who has been living with multiple sclerosis since 2016. This revelation highlights the challenges both women face as they navigate their health journeys together.

(UPDATED April 17, 2026 15:18 UTC)

Christina Applegate's memoir, "You With the Sad Eyes," has received high praise from her former co-star Chevy Chase, who described her as "incredibly talented." In a podcast episode from November 20th24, Applegate opened up about her struggles with multiple sclerosis, sharing that she often experiences severe pain and has difficulty with basic tasks, saying, “I can’t even pick up my phone sometimes, because now it’s traveled into my hands.” Applegate co-hosts the podcast “MeSsy” with Jamie-Lynn Sigler, who has also been living with multiple sclerosis since her diagnosis in 2016.

(UPDATED April 17, 2026 11:17 UTC)

Reports of Christina Applegate's hospitalization emerged on Thursday, prompting a response from her representative. While details remain unclear, there is speculation about whether her hospitalization is related to her multiple sclerosis. As of now, no further information has been provided regarding her condition.

(UPDATED April 17, 2026 09:20 UTC)

Christina Applegate, who is 54 years old, has opened up about her struggles with multiple sclerosis in her memoir, "You With the Sad Eyes." She candidly shares that simple tasks, like reaching for a cup of water or her phone, can be a challenge, and she admits to thinking about death daily while making arrangements for her future. Despite these health challenges, Applegate remains active in her professional life.

(UPDATED April 17, 2026 07:21 UTC)

Christina Applegate has opened up about the physical challenges she has faced due to multiple sclerosis. In a recent interview, she shared her experiences and the impact the condition has had on her life. Applegate's candid remarks have resonated with many, highlighting the struggles that come with this illness.

(UPDATED April 17, 2026 04:08 UTC)

Christina Applegate is currently hospitalized in Los Angeles, California, amid her ongoing battle with multiple sclerosis. She was admitted to the hospital in late March 20th26, although the exact reason for her hospitalization has not been disclosed. Reports from both the New York Post and TMZ confirm her condition and location.