Popular Fitness Supplement Shows Promise in Battling Depression

WHO:

NY Post - A doctor referred to creatine as "promising but not definitive" in the context of depression care.

Fox News - Researchers conducted a systematic review regarding the effects of creatine monohydrate on major depressive disorder.

WHAT:

NY Post - Creatine is suggested as a potential complement to existing depression treatments.

Fox News - The systematic review found that creatine monohydrate may help as an add-on treatment for major depressive disorder, but noted that the evidence is mixed.

WHY:

Fox News - The research indicates that there is a potential benefit of creatine in treating major depressive disorder, although the evidence supporting this is not conclusive.

(UPDATED July 7, 2026 15:56 UTC)

Recent research has highlighted creatine monohydrate as a potential complement to existing treatments for major depressive disorder, with a systematic review suggesting it may serve as an effective add-on therapy. However, experts caution that while the findings indicate a possible benefit, the evidence remains mixed and not definitive. A doctor involved in the discussion referred to creatine as "promising but not definitive" in the context of depression care.