Joe Manganiello Reveals Struggles With Long-term Health Issues

WHO:

ComingSoon.net - Joe Manganiello, actor known for his role in "Magic Mike"

NY Post - Joe Manganiello

WHAT:

US Magazine - Manganiello shared that in the days following the amputation of his large intestine, his weight began to plummet.

ComingSoon.net - Joe Manganiello released his book titled "Bloodlines: A Memoir"

ComingSoon.net - The memoir documents Manganiello's 7-year health battle with a mysterious autoimmune disorder

NY Post - Manganiello revealed he underwent an amputation due to his illness

WHERE:

ComingSoon.net - Manganiello shared graphic photos on X (formerly Twitter)

WHEN:

NY Post - The illness was first revealed over the summer in the synopsis of his memoir

WHY:

ComingSoon.net - The memoir aims to explore the challenges Manganiello faced during his health battle

HOW:

TMZ - Manganiello shared a photo of himself sitting in a hospital room, hooked up to medical equipment during his health battle.

ComingSoon.net - Manganiello posted several photos to accompany the first chapter of his book

(UPDATED October 16, 2026 02:05 UTC)

Manganiello revealed that after the amputation of his large intestine, he experienced a significant drop in weight. He shared this information during an interview with US Magazine. The health challenges he faced have been quite profound in the days following the surgery.

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(UPDATED October 15, 2026 23:00 UTC)

Manganiello has shared a photo of himself in a hospital room, connected to medical equipment as he continues to face his health battle. The image was posted at 22:01 UTC and has drawn attention from fans and followers. Many are rallying around him, offering their support during this challenging time.

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(UPDATED October 15, 2026 22:01 UTC)

Joe Manganiello has released his memoir titled "Bloodlines: A Memoir," which details his seven-year health battle with a mysterious autoimmune disorder, including a revelation that he underwent an amputation due to his illness. The actor shared graphic photos on X to accompany the first chapter of his book, which aims to explore the challenges he faced during this difficult time. The illness was first mentioned over the summer in the synopsis of the memoir, giving fans a glimpse into his struggles.